- HLA-E Monoclonal Antibody
- LSBio
- Pricing InfoSupplier PageView Company Product Page
- LS-B3729
- Unconjugated
- Purified by protein-A affinity chromatography. Greater than 95% by SDS-PAGE
- IgG1
- PBS, pH 7.4, 15 mM Sodium Azide
- MEM-E/06
- Mouse
- Human,Non-Human Primates
- HLA-E
- Flo, IHC, IHC-P, IP
- Monoclonal
- 0.05 mg
- major histocompatibility complex, class I, E
- HLA-6.2, QA1
Specifications/Features
Specificity: The antibody MEM-E/06 recognized native surface-expressed HLA-E, but not denaturated heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on many types of the human cells. The published results showed that the antibody cross-reacts with some classical MHC Class I molecules (HLA-A3, -A11, -B7). However, the recent Workshop I Session on the 3rd International Conference on HLA-G (Paris, July 2003) confirmed that the antibody exhibits much broader cross-reactivity classical MHC Class I antigens, namely with HLA-A24, -A32, -B8, -B15, -B27, -B35, -B44, -B54, -C3, -C4, -C5, -C7